Research Associate

Biomedical Micro Devices and Nanotechnology Lab seeks to hire a Postdoctoral Researcher to spearhead the development of innovative diagnostic biosensors. The successful candidate will focus on the end-to-end pipeline of biomarker discovery and sensor engineering, from molecular selection to high-fidelity analytical validation.

Key responsibilities and required expertise include:

• Aptamer Discovery & SELEX: Mastery of SELEX (Systematic Evolution of Ligands by Exponential Enrichment) methodologies to identify, select, and optimize high-affinity DNA/RNA aptamers for novel biomarker targets. Experience in post-SELEX characterization (e.g., determining Kd values) is essential.
• Biomarker Analysis (LC/MS): Proficiency in using LC/MS (Liquid Chromatography-Mass Spectrometry) to characterize and quantify biomarkers within complex biological matrices such as sweat, saliva, or blood, facilitating the transition from discovery to detection.
• Sensor Design & Engineering: A strong understanding of biochemistry and materials chemistry to integrate custom-developed aptamers into functional biosensor platforms (e.g., electrochemical).

Assay Development: The ability to independently design and execute complex, novel assay protocols for multiple biomarkers, ensuring robustness and sensitivity in real-world samples.